Endothelial cell regulation of systemic haemodynamics and metabolism acts through the HIF transcription factors

Endothelial cell regulation of systemic haemodynamics and metabolism acts through the HIF transcription factors

Abstract Background The vascular endothelium has important endocrine and paracrine roles, particularly in the regulation of vascular tone and immune function, and it has been implicated in the pathophysiology of a range of cardiovascular and inflammatory conditions. This study uses a series of trans...

Full description

Bibliographic Details
Main Authors: Simon Lambden, Andrew S. Cowburn, David Macias, Tessa A. C. Garrud, Bernardo J. Krause, Dino A. Giussani, Charlotte Summers, Randall S. Johnson
Format: Article
Language:English
Published: SpringerOpen 2021-06-01
Series:Intensive Care Medicine Experimental
Subjects:
HIF-1α
HIF-2α
Blood pressure
Haemodynamics
Metabolism
Vascular endothelium
Online Access:https://doi.org/10.1186/s40635-021-00390-y

Internet

https://doi.org/10.1186/s40635-021-00390-y

Similar Items