Pharmacokinetics of aminoglycoside antibiotics. Based on population pharmacokinetic data determination of the loading dose, maintenance dose and dosage interval

Aminoglycosides are natural or semisynthetic antibiotics derived from actinomycetes. They bind to the bacterial ribosome, leading to inhibition of protein synthesis. The spectrum of activity, rapid bactericidal activity, and favorable chemical and pharmacokinetic properties of aminoglycosides make t...

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Bibliographic Details
Main Authors: Arkadiusz Gruchlik, Marcin Kochan
Format: Article
Language:Polish
Published: Polish Pharmaceutical Society 2021-03-01
Series:Farmacja Polska
Subjects:
Online Access:https://www.ptfarm.pl/download/?file=File%2FFarmacja+Polska%2F2021%2F2%2F01_OG_Antybiotyki_aminoglikozydowe_n.pdf