Genomic expression analyses reveal lysosomal, innate immunity proteins, as disease correlates in murine models of a lysosomal storage disorder.

Genomic expression analyses reveal lysosomal, innate immunity proteins, as disease correlates in murine models of a lysosomal storage disorder.

Niemann-Pick Type C (NPC) disease is a rare, genetic, lysosomal disorder with progressive neurodegeneration. Poor understanding of the pathophysiology and a lack of blood-based diagnostic markers are major hurdles in the treatment and management of NPC and several additional, neurological lysosomal...

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Bibliographic Details
Main Authors: Md Suhail Alam, Michelle Getz, Innocent Safeukui, Sue Yi, Pamela Tamez, Jenny Shin, Peter Velázquez, Kasturi Haldar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3477142?pdf=render

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http://europepmc.org/articles/PMC3477142?pdf=render

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