Melatonin protects endothelial progenitor cells against AGE-induced apoptosis via autophagy flux stimulation and promotes wound healing in diabetic mice

Melatonin protects endothelial progenitor cells against AGE-induced apoptosis via autophagy flux stimulation and promotes wound healing in diabetic mice

Diabetes: Healing old wounds Melatonin, a sleep-regulating hormone, may speed wound healing in patients with diabetes by protecting blood-borne wound-healing cells known as endothelial progenitor cells (EPCs). In diabetes, EPCs become damaged, lose their capacity to migrate to wounds and form new ti...

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Bibliographic Details
Main Authors: Haiming Jin, Zengjie Zhang, Chengui Wang, Qian Tang, Jianle Wang, Xueqin Bai, Qingqing Wang, Majid Nisar, Naifeng Tian, Quan Wang, Cong Mao, Xiaolei Zhang, Xiangyang Wang
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0177-z

Internet

https://doi.org/10.1038/s12276-018-0177-z

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