A natural human monoclonal antibody targeting Staphylococcus Protein A protects against Staphylococcus aureus bacteremia.

Staphylococcus aureus can cause devastating and life-threatening infections. With the increase in multidrug resistant strains, novel therapies are needed. Limited success with active and passive immunization strategies have been attributed to S. aureus immune evasion. Here, we report on a monoclonal...

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Bibliographic Details
Main Authors: Avanish K Varshney, Galina A Kuzmicheva, Jian Lin, Kevin M Sunley, Rodney A Bowling, Tzu-Yu Kwan, Heather R Mays, Anu Rambhadran, Yanfeng Zhang, Rebecca L Martin, Michael C Cavalier, John Simard, Sushma Shivaswamy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5783355?pdf=render