Irinotecan-encapsulated double-reverse thermosensitive nanocarrier system for rectal administration

Irinotecan-encapsulated double-reverse thermosensitive nanocarrier system for rectal administration

Intravenously administered for the treatment of rectum cancer, irinotecan produces severe side effects due to very high plasma concentrations. A novel irinotecan-encapsulated double reverse thermosensitive nanocarrier system (DRTN) for rectal administration was developed as an alternative. The DRTN...

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Bibliographic Details
Main Authors: Fakhar ud Din, Ju Yeon Choi, Dong Wuk Kim, Omer Mustapha, Dong Shik Kim, Raj Kumar Thapa, Sae Kwang Ku, Yu Seok Youn, Kyung Taek Oh, Chul Soon Yong, Jong Oh Kim, Han-Gon Choi
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Drug Delivery
Subjects:
irinotecan
double reverse thermosensitive nanocarrier
rectal administration
burst effect
toxicity
anti-tumor efficacy
Online Access:http://dx.doi.org/10.1080/10717544.2016.1272651

Internet

http://dx.doi.org/10.1080/10717544.2016.1272651

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