A coupled discrete/continuum model for describing cancer-therapeutic transport in the lung.

We propose a computational simulation framework for describing cancer-therapeutic transport in the lung. A discrete vascular graph model (VGM) is coupled to a double-continuum model (DCM) to determine the amount of administered therapeutic agent that will reach the cancer cells. An alveolar cell car...

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Bibliographic Details
Main Authors: Karin Erbertseder, Johannes Reichold, Bernd Flemisch, Patrick Jenny, Rainer Helmig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3305605?pdf=render