Mechanisms of remyelination: recent insight from experimental models

Oligodendrocytes and myelin play essential roles in the vertebrate central nervous system. Demyelination disrupts saltatory nerve conduction, leading to axonal degeneration and neurological disabilities. Remyelination is a regenerative process that replaces lost myelin. However, remyelination is dis...

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Bibliographic Details
Main Authors: Tanaka Tatsuhide, Yoshida Shigetaka
Format: Article
Language:English
Published: De Gruyter 2014-08-01
Series:Biomolecular Concepts
Subjects:
Online Access:https://doi.org/10.1515/bmc-2014-0015