Improved drug carriage and protective potential against Cisplatin-induced toxicity using Boldine-loaded PLGA nanoparticles

Background: Cisplatin is a widely-used potent anti-cancer drug having severe side-effects precluding its sustained use. Objectives: Poly (lactide-co-glycolide) (PLGA)-nanoparticles loaded Boldine, an antioxidant ingredient of ethanolic extract of Boldo plant (Peumus boldus) was tested in cancer mice...

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Bibliographic Details
Main Authors: Jesmin Mondal, Mousumi Patra, Ashis Kumar Panigrahi, Anisur Rahman Khuda-Bukhsh
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Journal of Ayurveda and Integrative Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S0975947617303352