Impact of the Renin–Angiotensin System on the Endothelium in Vascular Dementia: Unresolved Issues and Future Perspectives

Impact of the Renin–Angiotensin System on the Endothelium in Vascular Dementia: Unresolved Issues and Future Perspectives

The effects of the renin–angiotensin system (RAS) surpass the renal and cardiovascular systems to encompass other body tissues and organs, including the brain. Angiotensin II (Ang II), the most potent mediator of RAS in the brain, contributes to vascular dementia via different mechanisms, including...

Full description

Bibliographic Details
Main Authors: Fatima Y. Noureddine, Raffaele Altara, Fan Fan, Andriy Yabluchanskiy, George W. Booz, Fouad A. Zouein
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
blood–brain barrier
ACE1
ACE2
AT2 receptor
Mas receptor
Ang(1–7)
Online Access:https://www.mdpi.com/1422-0067/21/12/4268

Internet

https://www.mdpi.com/1422-0067/21/12/4268

Similar Items