Effect of Yuzu (<i>Citrus junos</i>) Seed Limonoids and Spermine on Intestinal Microbiota and Hypothalamic Tissue in the Sandhoff Disease Mouse Model

Effect of Yuzu (<i>Citrus junos</i>) Seed Limonoids and Spermine on Intestinal Microbiota and Hypothalamic Tissue in the Sandhoff Disease Mouse Model

The effect of limonoids and spermine (Spm) extracted from yuzu (<i>Citrus junos</i>) seeds on the gut and the brain in a mouse model with Sandhoff disease (SD)was investigated. Wild-type and SD mice were fed a normal diet, or a diet supplemented with limonoid, Spm, or limonoid + Spm for...

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Bibliographic Details
Main Authors: Mayumi Minamisawa, Takuma Suzumura, Sudeep Bose, Tetsuyuki Taniai, Gota Kawai, Kyoko Suzuki, Akira Yamaguchi, Shoji Yamanaka
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Medical Sciences
Subjects:
Sandhoff disease
Yuzu (<i>Citrus junos</i>)
limonoids
spermine
intestinal microbiota
next-generation sequencing
Online Access:https://www.mdpi.com/2076-3271/9/1/17

Internet

https://www.mdpi.com/2076-3271/9/1/17

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