In vivo evaluation of cellular activity in αCaMKII heterozygous knockout mice using manganese-enhanced magnetic resonance imaging (MEMRI)

The alpha-calcium/calmodulin-dependent protein kinase II (αCaMKII) is a serine/threonine protein kinase predominantly expressed in the forebrain, especially in the postsynaptic density, and plays a key role in synaptic plasticity, learning and memory. αCaMKII heterozygous knockout (HKO) mice exhibit...

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Bibliographic Details
Main Authors: Satoko eHattori, Hideo eHagihara, Koji eOhira, Ichio eAoki, Tsuneo eSaga, Tetsuya eSuhara, Makoto eHiguchi, Tsuyoshi eMiyakawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Integrative Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnint.2013.00076/full