Disease-modifying effects of metabolic perturbations in ALS/FTLD

Abstract Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are two fatal neurodegenerative disorders with considerable clinical, pathological and genetic overlap. Both disorders are characterized by the accumulation of pathological protein aggregates that contain a num...

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Bibliographic Details
Main Authors: Ali Jawaid, Romesa Khan, Magdalini Polymenidou, Paul E. Schulz
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Molecular Neurodegeneration
Online Access:http://link.springer.com/article/10.1186/s13024-018-0294-0