Shear Stress-Induced Activation of von Willebrand Factor and Cardiovascular Pathology

Shear Stress-Induced Activation of von Willebrand Factor and Cardiovascular Pathology

The von Willebrand factor (vWF) is a plasma protein that mediates platelet adhesion and leukocyte recruitment to vascular injury sites and carries coagulation factor VIII, a building block of the intrinsic pathway of coagulation. The presence of ultra-large multimers of vWF in the bloodstream is ass...

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Bibliographic Details
Main Authors: Sergey Okhota, Ivan Melnikov, Yuliya Avtaeva, Sergey Kozlov, Zufar Gabbasov
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
von Willebrand factor
ADAMTS-13
atherosclerosis
atherothrombosis
coronary artery disease
Heyde’s syndrome
Online Access:https://www.mdpi.com/1422-0067/21/20/7804

Internet

https://www.mdpi.com/1422-0067/21/20/7804

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