The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon

NCOMMS-19-38235B Dorsal-ventral patterning of the mammalian telencephalon is fundamental to the formation of distinct functional regions. Here, the authors find that PcG proteins suppress BMP and Wnt signaling in a region-specific manner, allowing for proper Shh expression and development of the ven...

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Bibliographic Details
Main Authors: Hikaru Eto, Yusuke Kishi, Nayuta Yakushiji-Kaminatsui, Hiroki Sugishita, Shun Utsunomiya, Haruhiko Koseki, Yukiko Gotoh
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19556-5