Genetic Deletion of Polo-Like Kinase 2 Induces a Pro-Fibrotic Pulmonary Phenotype

Genetic Deletion of Polo-Like Kinase 2 Induces a Pro-Fibrotic Pulmonary Phenotype

Pulmonary fibrosis is the chronic-progressive replacement of healthy lung tissue by extracellular matrix, leading to the destruction of the alveolar architecture and ultimately death. Due to limited pathophysiological knowledge, causal therapies are still missing and consequently the prognosis is po...

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Bibliographic Details
Main Authors: Theresa A. Kant, Manja Newe, Luise Winter, Maximilian Hoffmann, Susanne Kämmerer, Erik Klapproth, Karolina Künzel, Mark P. Kühnel, Lavinia Neubert, Ali El-Armouche, Stephan R. Künzel
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
pulmonary fibrosis
PLK2
fibroblasts
Online Access:https://www.mdpi.com/2073-4409/10/3/617

Internet

https://www.mdpi.com/2073-4409/10/3/617

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