Negative Regulators of JAK/STAT Signaling in Rheumatoid Arthritis and Osteoarthritis
Elevated levels of pro-inflammatory cytokines are generally thought to be responsible for driving the progression of synovial joint inflammation in rheumatoid arthritis (RA) and osteoarthritis (OA). These cytokines activate several signal transduction pathways, including the Janus kinase/Signal Tran...
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Format: | Article |
Language: | English |
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MDPI AG
2017-02-01
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Series: | International Journal of Molecular Sciences |
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Online Access: | http://www.mdpi.com/1422-0067/18/3/484 |