Inhibition of PPARγ during Rat Pregnancy Causes Intrauterine Growth Restriction and Attenuation of Uterine Vasodilation

Decreased peroxisome proliferator-activated receptor gamma (PPARγ) activity is thought to have a major role in preeclampsia through abnormal placental development. However, the role of PPARγ in adaptation of the uteroplacental vasculature that may lead to placental hypoperfusion and fetal growth res...

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Bibliographic Details
Main Authors: Natalia I Gokina, Siu-Lung eChan, Abbie C Chapman, Karen eOppenheimer, Thomas eJetton, Marilyn J Cipolla
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00184/full