Potent bace-1 inhibitor design using pharmacophore modeling, <it>in silico</it> screening and molecular docking studies
<p>Abstract</p> <p>Background</p> <p>Beta-site amyloid precursor protein cleaving enzyme (BACE-1) is a single-membrane protein belongs to the aspartyl protease class of catabolic enzymes. This enzyme involved in the processing of the amyloid precursor protein (APP). The...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-02-01
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| Series: | BMC Bioinformatics |