Personalise vitamin D3 using physiologically based pharmacokinetic modelling
Abstract Plasma concentration of vitamin D3 metabolite 25‐hydroxyvitamin D3 (25(OH)D3) is variable among individuals. The objective of this study is to establish an accurate model for 25(OH)D3 pharmacokinetics (PKs) to support selection of a suitable dose regimen for an individual. We collated vitam...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-07-01
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Series: | CPT: Pharmacometrics & Systems Pharmacology |
Online Access: | https://doi.org/10.1002/psp4.12640 |