Phenotypic and genotypic characterization of daptomycin-resistant methicillin-resistant Staphylococcus aureus strains: relative roles of mprF and dlt operons.

Development of in vivo daptomycin resistance (DAP-R) among Staphylococcus aureus clinical isolates, in association with clinical treatment failures, has become a major therapeutic problem. This issue is especially relevant to methicillin-resistant S. aureus (MRSA) strains in the context of invasive...

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Main Authors: Nagendra N Mishra, Arnold S Bayer, Christopher Weidenmaier, Timo Grau, Stefanie Wanner, Stefania Stefani, Viviana Cafiso, Taschia Bertuccio, Michael R Yeaman, Cynthia C Nast, Soo-Jin Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4166420?pdf=render