Evaluation of a 27-gene inherited cancer panel across 630 consecutive patients referred for testing in a clinical diagnostic laboratory

Evaluation of a 27-gene inherited cancer panel across 630 consecutive patients referred for testing in a clinical diagnostic laboratory

Abstract Background Extensive clinical and genetic heterogeneity of inherited cancers has allowed multi-gene panel testing to become an efficient means for identification of patients with an inherited predisposition to a broad spectrum of syndromic and nonsyndromic forms of cancer. This study report...

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Bibliographic Details
Main Authors: Sabrina A. Gardner, Katelyn S. Weymouth, Wei S. Kelly, Ekaterina Bogdanova, Wenjie Chen, Daniel Lupu, Joshua Suhl, Qiandong Zeng, Ute Geigenmüller, Debbie Boles, Patricia M. Okamoto, Geraldine McDowell, Melissa A. Hayden, Narasimhan Nagan
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
Inherited cancer panel
VUS
HBOC
Lynch syndrome
CMMRD
Variant classification
Online Access:http://link.springer.com/article/10.1186/s13053-017-0083-8

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http://link.springer.com/article/10.1186/s13053-017-0083-8

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