Corticosterone Treatment and Incubation Time After Contextual Fear Conditioning Synergistically Induce Fear Memory Generalization in Neuropeptide S Receptor-Deficient Mice

Corticosterone Treatment and Incubation Time After Contextual Fear Conditioning Synergistically Induce Fear Memory Generalization in Neuropeptide S Receptor-Deficient Mice

Fear memory generalization is a learning mechanism that promotes flexible fear responses to novel situations. While fear generalization has adaptive value, overgeneralization of fear memory is a characteristic feature of the pathology of anxiety disorders. The neuropeptide S (NPS) receptor (NPSR) ha...

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Bibliographic Details
Main Authors: Malgorzata H. Kolodziejczyk, Markus Fendt
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Neuroscience
Subjects:
neuropeptide S
memory generalization
contextual fear
corticosterone
post-traumatic stress disorder
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00128/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.00128/full

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