Modulation of mitochondrial nucleoid structure during aging and by mtDNA content in Drosophila

Modulation of mitochondrial nucleoid structure during aging and by mtDNA content in Drosophila

Mitochondrial DNA (mtDNA) encodes gene products that are essential for oxidative phosphorylation. They organize as higher order nucleoid structures (mtNucleoids) that were shown to be critical for the maintenance of mtDNA stability and integrity. While mtNucleoid structures are associated with cellu...

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Bibliographic Details
Main Authors:	Li-jie Wang, Tian Hsu, Hsiang-ling Lin, Chi-yu Fu
Format:	Article
Language:	English
Published:	The Company of Biologists 2021-06-01
Series:	Biology Open
Subjects:	mitochondrial dna mitochondrial nucleoid transcription factor a (tfam) mitochondrial rna polymerase (mtrnapol) mitochondrial transcription factor b2 (mttfb2)
Online Access:	http://bio.biologists.org/content/10/6/bio058553

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