Modulation of mitochondrial nucleoid structure during aging and by mtDNA content in Drosophila
Mitochondrial DNA (mtDNA) encodes gene products that are essential for oxidative phosphorylation. They organize as higher order nucleoid structures (mtNucleoids) that were shown to be critical for the maintenance of mtDNA stability and integrity. While mtNucleoid structures are associated with cellu...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2021-06-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/10/6/bio058553 |