Maternal Brown Fat Thermogenesis Programs Glucose Tolerance in the Male Offspring

Maternal Brown Fat Thermogenesis Programs Glucose Tolerance in the Male Offspring

Summary: Environmental temperature is a driving factor in evolution, and it is commonly assumed that metabolic adaptations to cold climates are the result of transgenerational selection. Here, we show in mice that even minor changes in maternal thermogenesis alter the metabolic phenotype already in...

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Bibliographic Details
Main Authors: Rebecca Oelkrug, Christin Krause, Beate Herrmann, Julia Resch, Sogol Gachkar, Alexander T. El Gammal, Stefan Wolter, Oliver Mann, Henrik Oster, Henriette Kirchner, Jens Mittag
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Cell Reports
Subjects:
thermogenesis
brown adipose tissue
uncoupling protein 1
pregnancy
gestation
temperature
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720313401

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http://www.sciencedirect.com/science/article/pii/S2211124720313401

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