Ferryl Hemoglobin and Heme Induce A<sub>1</sub>-Microglobulin in Hemorrhaged Atherosclerotic Lesions with Inhibitory Function against Hemoglobin and Lipid Oxidation

Ferryl Hemoglobin and Heme Induce A<sub>1</sub>-Microglobulin in Hemorrhaged Atherosclerotic Lesions with Inhibitory Function against Hemoglobin and Lipid Oxidation

Infiltration of red blood cells into atheromatous plaques and oxidation of hemoglobin (Hb) and lipoproteins are implicated in the pathogenesis of atherosclerosis. α<sub>1</sub>-microglobulin (A1M) is a radical-scavenging and heme-binding protein. In this work, we examined the origin and...

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Bibliographic Details
Main Authors: Dávid Pethő, Tamás Gáll, Zoltán Hendrik, Annamária Nagy, Lívia Beke, Attila Péter Gergely, Gábor Méhes, Csaba Tóth, Magnus Gram, Bo Åkerström, György Balla, József Balla
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
atherosclerosis
hemorrhage
α<sub>1</sub>-microglobulin
hemoglobin oxidation
heme
Ferryl Hemoglobin
Online Access:https://www.mdpi.com/1422-0067/22/13/6668

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https://www.mdpi.com/1422-0067/22/13/6668

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