Quantitative proteomic and interaction network analysis of cisplatin resistance in HeLa cells.

Cisplatin along with other platinum based drugs are some of the most widely used chemotherapeutic agents. However drug resistance is a major problem for the successful chemotherapeutic treatment of cancer. Current evidence suggests that drug resistance is a multifactorial problem due to changes in t...

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Bibliographic Details
Main Authors: Juan D Chavez, Michael R Hoopmann, Chad R Weisbrod, Kohji Takara, James E Bruce
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3102677?pdf=render