The C-Type Lectin Receptor DC-SIGN Has an Anti-Inflammatory Role in Human M(IL-4) Macrophages in Response to Mycobacterium tuberculosis

The C-Type Lectin Receptor DC-SIGN Has an Anti-Inflammatory Role in Human M(IL-4) Macrophages in Response to Mycobacterium tuberculosis

DC-SIGN (CD209/CLEC4L) is a C-type lectin receptor (CLR) that serves as a reliable cell-surface marker of interleukin 4 (IL-4)-activated human macrophages [M(IL-4)], which historically represent the most studied subset within the M2 spectrum of macrophage activation. Although DC-SIGN plays important...

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Bibliographic Details
Main Authors: Geanncarlo Lugo-Villarino, Anthony Troegeler, Luciana Balboa, Claire Lastrucci, Carine Duval, Ingrid Mercier, Alan Bénard, Florence Capilla, Talal Al Saati, Renaud Poincloux, Ivanela Kondova, Frank A. W. Verreck, Céline Cougoule, Isabelle Maridonneau-Parini, Maria del Carmen Sasiain, Olivier Neyrolles
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
macrophages
Mycobacterium tuberculosis
DC-SIGN
C-type lectin receptors
anti-inflammatory
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01123/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01123/full

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