Glycogen Synthase Kinase 3β Enhances Hepatitis C Virus Replication by Supporting miR-122

Glycogen Synthase Kinase 3β Enhances Hepatitis C Virus Replication by Supporting miR-122

Hepatitis C virus (HCV) infection is associated with alterations in host lipid and insulin signaling cascades, which are partially explained by a dependence of the HCV life cycle on key molecules in these metabolic pathways. Yet, little is known on the role in the HCV life cycle of glycogen synthase...

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Bibliographic Details
Main Authors: Maged Saleh, Sabrina Rüschenbaum, Christoph Welsch, Stefan Zeuzem, Darius Moradpour, Jérôme Gouttenoire, Christian M. Lange
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Microbiology
Subjects:
GSK3α
GSK3β
hepatitis E virus
host-targeting antivirals
insulin resistance
miR-122
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02949/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.02949/full

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