Evaluation of the Combined Effect of 2ME2 and Co on the Inducement of DNA Damage by IUdR in a Spheroid Model of the U87MG Glioblastoma Cancer Cell Line Using Alkaline Comet Assay

Evaluation of the Combined Effect of 2ME2 and Co on the Inducement of DNA Damage by IUdR in a Spheroid Model of the U87MG Glioblastoma Cancer Cell Line Using Alkaline Comet Assay

Objective: In this study, we investigated the combined effect of 2-Methoxyestradiol (2ME2)and 60Co on the cytogenetic damage of iododeoxyuridine (IUdR) in the spheroid model ofU87MG glioblastoma cancer cell lines by alkaline comet assay.Materials and Methods: U87MG cells were cultured as spheroids w...

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Bibliographic Details
Main Authors: Ali Neshasteh-Riz, Seyed Rabi Mahdavi, Samideh Khoei, Sara Delfan
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2011-01-01
Series:Cell Journal
Subjects:
Iododeoxyuridinre
DNA Damage
HIF-1Alpha
2-Methoxyestradiol
Comet
Online Access:http://www.celljournal.org/library/upload/article/af_2285444223845624662322274543555736324432Khoei.pdf

Internet

http://www.celljournal.org/library/upload/article/af_2285444223845624662322274543555736324432Khoei.pdf

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