Synthesis and structure of vanillin azomethines

Synthesis and structure of vanillin azomethines

Vanillin is most prominent as the principal flavor and aroma compound in vanilla. Vanillin has been used as a chemical intermediate in the production of pharmaceuticals and other fine chemicals.The two intermediates, assigned as intermediates I and II, were prepared by using vanillin and 1-butylbrom...

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Bibliographic Details
Main Authors: Jasmina M. Jovanović, Sandra S. Konstantinović, Budimir V. Konstantinović
Format: Article
Language:English
Published: Association of the Chemical Engineers of Serbia 2009-10-01
Series:Chemical Industry and Chemical Engineering Quarterly
Subjects:
Vanillin is most prominent as the principal flavor and aroma compound in vanilla. Vanillin has been used as a chemical intermediate in the production of pharmaceuticals and other fine chemicals.The two intermediates
assigned as intermediates I and II
were prepared by using vanillin and 1-butylbromide or 2-chloroacetic acid
respectively. The condensation of intermediates with 2
3- -diaminopyridine gave azomethines. Their structure was established by using elemental microanalysis
as well as UV/Vis
FTIR and 1H-NMR spectra. Synthesized compounds were tested for their antifungal activity against Candida albicans
Candida lipolytica and Sacharomyces cerevisiae
Online Access:http://www.ache.org.rs/CICEQ/2009/No4/CICEQ_Vol15_%20No4_pp279-281_Oct-Dec_2009.pdf

Internet

http://www.ache.org.rs/CICEQ/2009/No4/CICEQ_Vol15_%20No4_pp279-281_Oct-Dec_2009.pdf

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