New in vitro phenotypic assay for epilepsy: fluorescent measurement of synchronized neuronal calcium oscillations.

Research in the epilepsy field is moving from a primary focus on controlling seizures to addressing disease pathophysiology. This requires the adoption of resource- and time-consuming animal models of chronic epilepsy which are no longer able to sustain the testing of even moderate numbers of compou...

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Bibliographic Details
Main Authors: Nathalie Pacico, Ana Mingorance-Le Meur
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3885603?pdf=render