Reduced connectivity in the self-processing network of schizophrenia patients with poor insight.

Lack of insight (unawareness of illness) is a common and clinically relevant feature of schizophrenia. Reduced levels of self-referential processing have been proposed as a mechanism underlying poor insight. The default mode network (DMN) has been implicated as a key node in the circuit for self-ref...

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Bibliographic Details
Main Authors: Edith J Liemburg, Lisette van der Meer, Marte Swart, Branislava Curcic-Blake, Richard Bruggeman, Henderikus Knegtering, André Aleman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3415395?pdf=render