An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples

An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples

SUMMARY Recent studies indicated that sortilin-related receptor 1 (SORL1) is a risk gene for late-onset Alzheimer's disease (AD), although its role in the aetiology and/or progression of this disorder is not fully understood. Here, we report the finding of a non-coding (nc) RNA (hereafter refer...

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Bibliographic Details
Main Authors: Eleonora Ciarlo, Sara Massone, Ilaria Penna, Mario Nizzari, Arianna Gigoni, Giorgio Dieci, Claudio Russo, Tullio Florio, Ranieri Cancedda, Aldo Pagano
Format: Article
Language:English
Published: The Company of Biologists 2013-03-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/6/2/424

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http://dmm.biologists.org/content/6/2/424

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