No observed effect on brain vasculature of Alzheimer’s disease-related mutations in the zebrafish presenilin 1 gene

Abstract Previously, we found that brains of adult zebrafish heterozygous for Alzheimer’s disease-related mutations in their presenilin 1 gene (psen1, orthologous to human PSEN1) show greater basal expression levels of hypoxia responsive genes relative to their wild type siblings under normoxia, sug...

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Bibliographic Details
Main Authors: Karissa Barthelson, Morgan Newman, Cameron J. Nowell, Michael Lardelli
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Molecular Brain
Subjects:
Online Access:https://doi.org/10.1186/s13041-021-00734-5