PITX2 Enhances the Regenerative Potential of Dystrophic Skeletal Muscle Stem Cells

Summary: Duchenne muscular dystrophy (DMD), one of the most lethal genetic disorders, involves progressive muscle degeneration resulting from the absence of DYSTROPHIN. Lack of DYSTROPHIN expression in DMD has critical consequences in muscle satellite stem cells including a reduced capacity to gener...

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Bibliographic Details
Main Authors: Daniel Vallejo, Francisco Hernández-Torres, Estefanía Lozano-Velasco, Lara Rodriguez-Outeiriño, Alejandra Carvajal, Carlota Creus, Diego Franco, Amelia Eva Aránega
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221367111830136X