Regulation of X-linked gene expression during early mouse development by Rlim

Regulation of X-linked gene expression during early mouse development by Rlim

Mammalian X-linked gene expression is highly regulated as female cells contain two and male one X chromosome (X). To adjust the X gene dosage between genders, female mouse preimplantation embryos undergo an imprinted form of X chromosome inactivation (iXCI) that requires both Rlim (also known as Rnf...

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Bibliographic Details
Main Authors: Feng Wang, JongDae Shin, Jeremy M Shea, Jun Yu, Ana Bošković, Meg Byron, Xiaochun Zhu, Alex K Shalek, Aviv Regev, Jeanne B Lawrence, Eduardo M Torres, Lihua J Zhu, Oliver J Rando, Ingolf Bach
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-09-01
Series:eLife
Subjects:
single embryo RNA-seq
mouse preimplantation development
X chromosome inactivation
X upregulation
Rlim/Rnf12
Xist
Online Access:https://elifesciences.org/articles/19127

Internet

https://elifesciences.org/articles/19127

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