TDP-43 Potentiates Alpha-synuclein Toxicity to Dopaminergic Neurons in Transgenic Mice

TDP-43 Potentiates Alpha-synuclein Toxicity to Dopaminergic Neurons in Transgenic Mice

<p>TDP-43 and &#945;-synuclein are two disease proteins involved in a wide range of neurodegenerative diseases. While TDP-43 proteinopathy is considered a pathologic hallmark of sporadic amyotrophic lateral sclerosis and frontotemporal lobe degeneration, &#945;-synuclein is a major com...

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Bibliographic Details
Main Author: Tian Tian, Cao Huang, Jianbin Tong, Ming Yang, Hongxia Zhou, Xu-Gang Xia
Format: Article
Language:English
Published: Ivyspring International Publisher 2011-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v07p0234.htm

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http://www.biolsci.org/v07p0234.htm

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