Diminished Sphingolipid Metabolism, a Hallmark of Future Type 2 Diabetes Pathogenesis, Is Linked to Pancreatic β Cell Dysfunction

Diminished Sphingolipid Metabolism, a Hallmark of Future Type 2 Diabetes Pathogenesis, Is Linked to Pancreatic β Cell Dysfunction

Summary: Gestational diabetes mellitus (GDM) is the top risk factor for future type 2 diabetes (T2D) development. Ethnicity profoundly influences who will transition from GDM to T2D, with high risk observed in Hispanic women. To better understand this risk, a nested 1:1 pair-matched, Hispanic-specif...

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Bibliographic Details
Main Authors: Saifur R. Khan, Yousef Manialawy, Andreea Obersterescu, Brian J. Cox, Erica P. Gunderson, Michael B. Wheeler
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:iScience
Subjects:
Pathophysiology
Human Physiology
Genomics
Bioinformatics
Systems Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220307586

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http://www.sciencedirect.com/science/article/pii/S2589004220307586

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