33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways

33-kDa ANXA3 isoform contributes to hepatocarcinogenesis via modulating ERK, PI3K/Akt-HIF and intrinsic apoptosis pathways

Introduction: As a member of annexin family proteins, annexin A3 (ANXA3) has 36-kDa and 33-kDa isoforms. ANXA3 plays crucial roles in the tumorigenesis, aggressiveness and drug-resistance of cancers. However, previous studies mainly focused on the role of total ANXA3 in cancers without distinguishin...

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Bibliographic Details
Main Authors: Chunmei Guo, Nannan Li, Chengyong Dong, Liming Wang, Zhaopeng Li, Qinlong Liu, Qinglai Ma, Frederick T. Greenaway, Yuxiang Tian, Lihong Hao, Shuqing Liu, Ming-Zhong Sun
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Journal of Advanced Research
Subjects:
Hepatocarcinoma
33-kDa ANXA3
Tumorigenesis
Angiogenesis
Chemoresistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123220302307

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http://www.sciencedirect.com/science/article/pii/S2090123220302307

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