Maternal nutrition induces pervasive gene expression changes but no detectable DNA methylation differences in the liver of adult offspring.

Maternal nutrition induces pervasive gene expression changes but no detectable DNA methylation differences in the liver of adult offspring.

Epidemiological and animal studies have shown that maternal diet can influence metabolism in adult offspring. However, the molecular mechanisms underlying these changes remain poorly understood. Here, we characterize the phenotypes induced by maternal obesity in a mouse model and examine gene expres...

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Bibliographic Details
Main Authors: Matthew V Cannon, David A Buchner, James Hester, Hadley Miller, Ephraim Sehayek, Joseph H Nadeau, David Serre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3940881?pdf=render

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http://europepmc.org/articles/PMC3940881?pdf=render

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