VKORC1 gene (vitamin K epoxide reductase) polymorphisms are associated with cardiovascular disease in chronic kidney disease patients on hemodialysis

Vitamin K is necessary for the carboxylation of clotting factors and matrix Gla protein (MGP). Vitamin K epoxide reductase (VKOR) is the enzyme responsible for recirculation of Vitamin K increasing its tissue availability. Polymorphisms of VKOR may alter the function of MGP, thereby influencing vasc...

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Bibliographic Details
Main Authors: Noha A Osman, Nevine El-Abd, Mohamed Nasrallah
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Saudi Journal of Kidney Diseases and Transplantation
Online Access:http://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=5;spage=908;epage=915;aulast=Osman