Therapeutic Target and Cell-signal Communication of Chlorpromazine and Promethazine in Attenuating Blood–Brain Barrier Disruption after Ischemic Stroke

Ischemic stroke destroys blood–brain barrier (BBB) integrity. There are currently no effective treatments available in the clinical setting. Post-ischemia treatment with phenothiazine drugs [combined chlorpromazine and promethazine (C+P)] has been shown to be neuroprotective in stroke. The present s...

Full description

Bibliographic Details
Main Authors: Fengwu Li, Xiaokun Geng, James Yip, Yuchuan Ding
Format: Article
Language:English
Published: SAGE Publishing 2019-02-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689718819443