Endothelial Glycocalyx Disorders May Be Associated With Extended Inflammation During Endotoxemia in a Diabetic Mouse Model

In diabetes mellitus (DM) patients, the morbidity of infectious disease is increased, and these infections can easily progress from local to systemic infection. Sepsis is a characteristic of organ failure related to microcirculation disorders resulting from endothelial cell injury, whose most freque...

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Bibliographic Details
Main Authors: So Sampei, Hideshi Okada, Hiroyuki Tomita, Chihiro Takada, Kodai Suzuki, Takamasa Kinoshita, Ryo Kobayashi, Hirotsugu Fukuda, Yuki Kawasaki, Ayane Nishio, Hirohisa Yano, Isamu Muraki, Yohei Fukuda, Keiko Suzuki, Nagisa Miyazaki, Takatomo Watanabe, Tomoaki Doi, Takahiro Yoshida, Akio Suzuki, Shozo Yoshida, Shigeki Kushimoto, Shinji Ogura
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.623582/full