Nox2 contributes to hyperinsulinemia-induced redox imbalance and impaired vascular function

Nox2 contributes to hyperinsulinemia-induced redox imbalance and impaired vascular function

Insulin resistance promotes vascular endothelial dysfunction and subsequent development of cardiovascular disease. Previously we found that skeletal muscle arteriolar flow-induced dilation (FID) was reduced following a hyperinsulinemic clamp in healthy adults. Therefore, we hypothesized that hyperin...

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Bibliographic Details
Main Authors: Abeer M. Mahmoud, Mohamed M. Ali, Edwin R. Miranda, Jacob T. Mey, Brian K. Blackburn, Jacob M. Haus, Shane A. Phillips
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Redox Biology
Subjects:
Insulin
NADPH oxidase
Nitric oxide
Superoxide
Microvascular
Endothelial cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717302148

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http://www.sciencedirect.com/science/article/pii/S2213231717302148

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