Multidrug-resistant tuberculosis (MDR-TB) strain infection in macaques results in high bacilli burdens in airways, driving broad innate/adaptive immune responses

Multidrug-resistant tuberculosis (MDR-TB) strain infection in macaques results in high bacilli burdens in airways, driving broad innate/adaptive immune responses

Abstract Tuberculosis (TB) has become the most deadly infectious diseases due to epidemics of HIV/AIDS and multidrug-resistant/extensively drug-resistant TB (MDR-/XDR-TB). Although person-to-person transmission contributes to MDR-TB, it remains unknown whether infection with MDR strains resembles in...

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Bibliographic Details
Main Authors: Enzhuo Yang, Rui Yang, Ming Guo, Dan Huang, Wandang Wang, Zhuoran Zhang, Crystal Chen, Feifei Wang, Wenzhe Ho, Ling Shen, Heping Xiao, Zheng W. Chen, Hongbo Shen
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Emerging Microbes and Infections
Online Access:http://link.springer.com/article/10.1038/s41426-018-0213-z

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http://link.springer.com/article/10.1038/s41426-018-0213-z

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