A SMYD3/ITGB6/TGFβ1 Positive Feedback Loop Promotes the Invasion and Adhesion of Ovarian Cancer Spheroids

A SMYD3/ITGB6/TGFβ1 Positive Feedback Loop Promotes the Invasion and Adhesion of Ovarian Cancer Spheroids

BackgroundImplantation metastasis is the main means of dissemination in ovarian cancer. Our previous studies showed that SET and MYND domain-containing protein 3 (SMYD3) expression was higher in ovarian cancer spheroids than in monolayers. SMYD3 enhancement of spheroid invasion and adhesion is media...

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Bibliographic Details
Main Authors: Yahui Jiang, Tianyu Zhou, Yiwen Shi, Weiwei Feng, Tianjiao Lyu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
ovarian cancer spheroids
metastasis
SMYD3
ITGB6
TGFβ1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.690618/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.690618/full

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