Non-linear Optimization of Parameters in Hill Kinetics

A novel least squares optimization of parameters in Hill enzyme kinetics has been developed. The method is based on transformation into “Michaelis-Menten like” type of equation with guaranteed convergence and the initial guess equal to zero. By using this approach, a three parameters non-linear opti...

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Bibliographic Details
Main Author: Željko Jeričević
Format: Article
Language:English
Published: Croatian Chemical Society 2016-06-01
Series:Croatica Chemica Acta
Online Access:http://hrcak.srce.hr/file/248246