Rictor Deficiency Aggravates Hepatic Ischemia/Reperfusion Injury in Mice by Suppressing Autophagy and Regulating MAPK Signaling

Rictor Deficiency Aggravates Hepatic Ischemia/Reperfusion Injury in Mice by Suppressing Autophagy and Regulating MAPK Signaling

Background/Aims: The role of Rictor in hepatic ischemia/reperfusion (I/R) injury remains unknown. Here, we comprehensively examined the role of Rictor in hepatic I/R injury. Methods: We studied the expression of Rictor during hepatic I/R injury. The regulatory effects of Rictor on inflammatory respo...

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Bibliographic Details
Main Authors: Dongwei Xu, Jianjun Zhu, Seogsong Jeong, Dawei Li, Xiangwei Hua, Lifeng Huang, Jianjun Zhang, Yi Luo, Qiang Xia
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Hepatic ischemia/reperfusion injury
MTORC2
Rictor
Autophagy
Online Access:https://www.karger.com/Article/FullText/488165

Internet

https://www.karger.com/Article/FullText/488165

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